Impact of metabolic syndrome on the viability of human spermatozoa: a cross-sectional descriptive study in men from infertile couples
, Tuyet Nguyen Thi Hiep, , , , , Oct-2021, In: Basic and Clinical Andrology, 31, 22, p. 1-9
Overview
Abstract:
Background:A direct association between metabolic syndrome (MetS) and sperm production/function has beenproposed. In this cross-sectional study, we aimed to determine the impact of MetS on sperm survival. Men frominfertile couples treated at Hue University Hospital, Vietnam, were enrolled in this study, which spanned theOctober 2018 to October 2020 period. The general characteristics of the patients, including body mass index (BMI),waist-to-hip ratio (WHR), the levels of different biochemicals, and semen parameters were determined, and spermsurvival tests (SSTs) were performed. The modified National Cholesterol Education Program (NCEP) Adult TreatmentPanel (ATP) III for the Asian population was used for MetS diagnosis.Results:Men with an abnormal waist circumference (≥90 cm) showed a higher rate of abnormal SST results (30.1%vs. 16.7%,p= 0.012). The frequency of abnormal SST results in patients with MetS (72.3%) was significantly higherthan that in individuals without MetS (53.4%) (p= 0.02). Furthermore, the percentage of abnormal SST results inpatients with MetS and with BMI≥23 was significantly higher than those in individuals without MetS (77.1% vs.55.2%,p= 0.03). Weak negative correlations were also observed between the patients’age and the SST results.Conclusion:Sperm viability was lower in men with MetS. We also observed that age and BMI were independentfactors associated with abnormal SST
Keyword(s): Spermatozoa, Survival test, Infertility, Metabolic syndrome
| Pages (from-to) | 1-9 |
| Journal | Basic and Clinical Andrology |
| Volume | 31 |
| Issue number | 22 |
| Publication status | Published - Oct-2021 |
| ISBN | 20514190 |