Long-term outcomes of kidney transplantation in a transfusion-dependent alpha-thalassemia patient
Tu Tran Tuan, Jul-2025, In: CEN Case Reports, ., p. .
Overview
Abstract:
The improved survival rates of patients with thalassemia have led to the identification of new complications, including renal diseases. In cases of end-stage kidney disease, kidney transplantation is regarded as the preferred treatment. However, research on kidney transplantation in thalassemia patients remains limited. We present the case of a transfusion-dependent alpha-thalassemia patient who underwent kidney transplantation due to end-stage kidney disease and maintained stable graft function over a 7-year follow-up period. Notably, 7 years post-transplant, the patient demonstrated a creatinine level of 128 µmol/L and a glomerular filtration rate of 64 mL/min/1.73 m2. Despite requiring blood transfusions every 3 months, the patient’s renal function remained stable throughout the follow-up period. This case highlights the viability and effectiveness of kidney transplantation as a long-term treatment option for patients with alpha-thalassemia and end-stage kidney disease, as well as the need for further research to better understand the long-term outcomes and challenges in this population.
Keyword(s): Alpha-thalassemia · End-stage kidney disease · Kidney transplantation · Transfusion-dependent thalassemia
| Article number | . |
| Journal | CEN Case Reports |
| Volume | . |
| Publication status | Published - Jul-2025 |
| ISBN | 2192-4449 |