The basic objective of physical education activities at university is physical development which is oriented to be suitable with students’ characteristics, needs, training majors and social realities. By using the basic scientific research methods for Physical education, this study aimed at selecting on-site exercises for physical development for the second-year students majoring in General Practitioners at University of Medicine and Pharmacy - Thai Nguyen University. Research results showed that the physical condition of the study group is still limited. The research has selected 10 suitable and reliable on-the-job exercises in the interview process (p<0.05). The initial post-experiment results obtained a positive growth rate in all indicators, at the same time, the experimental effect of the selected exercises was significantly improved in the development of endurance qualities in the experimental group (calculated > ttable at the probability threshold P < 0.05).