This study was conducted to develop modules in ESP for Dentistry students based on their language needs as students and in their job in the workplace. The modules highlighted the development of Speaking and Listening skills, although other skills are integrated. These modules were validated by teachers and empirically tested to two sections of freshmen students of Dentistry. Module evaluation indicated that the ESP modules were acceptable in terms of format, objectives and content, examples and illustrations, and self-assessment questions. Results between the pretest and posttest scores of the students significantly differed – in the overall scores and the disaggregated scores in speaking and listening. The English for Specific Purposes modules for Dentistry students are valid and reliable for use in the development of speaking and listening skills to the students. Moreover, the use of task-based approach and natural approach in presenting language through modules is suitable for the students.